Product Name: CAZIP Antibody
Species Reactivity: Human, Mouse
Tested Applications: ELISA, IF, IHC-P, WB
Applications: CAZIP antibody can be used for detection of CAZIP by Western blot at 0.5 – 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: CAZIP antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human CAZIP.The immunogen is located within amino acids 1300 – 1350 of CAZIP.
Host Species: Rabbit
Purification: CAZIP Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 1642-54-2
Product: Diethylcarbamazine (citrate)
Buffer: CAZIP Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: CAZIP antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: CAZIP Antibody: ICIS, CAZIP, TIP150, KIAA0774, Microtubule-associated tumor suppressor candidate 2, Cardiac zipper protein, Tracking protein of 150 kDa
Accession NO.: NP_001028774
Protein Ino: 140161498
Official Symbol: MTUS2
Geneid: 23281
Background: CAZIP Antibody: CAZIP, also known as TIP150, contains a leucine-zipper domain at the C-terminus and has at least three isoforms. CAZIP is expressed in heart during early cardiac development and in parts of the nervous system in later embryonic development. It is thought to bind microtubules and facilitate the end-binding protein 1 (EB1)-dependent loading of MCAK onto microtubules plus ends and orchestrates the dynamics at the plus end of microtubules. CAZIP may regulate the dynamics of microtubules at their growing distal tip.
PubMed ID:http://aac.asm.org/content/43/6/1480.abstract
