Product Name: C2TA Antibody
Species Reactivity: Mouse
Tested Applications: ELISA, WB
Applications: C2TA antibody can be used for detection of C2TA by ELISA at 1:62500. C2TA antibody can be used for detection of C2TA by western blot at 0.125 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 119 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of mouse C2TA.
Host Species: Rabbit
Purification: Antibody is purified by peptide affinity chromatography method.
Physical State: Lyophilized
CAS NO.: 1672665-49-4
Product: PT-2385
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store C2TA antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: C2TA, C2ta, Gm9475, EG669998
Accession NO.: NP_031601
Protein Ino: 6671654
Official Symbol: Ciita
Geneid: 12265
Background: C2ta is essential for transcriptional activity of the HLA class II promoter; activation is via the proximal promoter. No DNA binding of in vitro translated CIITA was detected. C2ta may act in a coactivator-like fashion through protein-protein interactions by contacting factors binding to the proximal MHC class II promoter, to elements of the transcription machinery, or both. Alternatively it may activate HLA class II transcription by modifying proteins that bind to the MHC class II promoter
PubMed ID:http://aac.asm.org/content/42/10/2626.abstract
