Product Name: BOK Antibody
Species Reactivity: Human
Tested Applications: ELISA, IHC-P
Applications: BOK antibody can be used for detection of BOK by immunohistochemistry at 5 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: BOK antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human BOK.The immunogen is located within the first 50 amino acids of BOK.
Host Species: Rabbit
Purification: BOK Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 1165910-22-4
Product: LGD-4033
Buffer: BOK Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: BOK antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: BOK Antibody: BOKL, BCL2L9, Bcl-2-related ovarian killer protein, Bcl-2-like protein 9, hBOK
Accession NO.: AAH06203
Protein Ino: 14210524
Official Symbol: BOK
Geneid: 666
Background: BOK Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. BOK, a pro-apoptotic Bcl-2 family member, was initially identified in the ovary, and was found to interact with other Bcl-2 family members such as Mcl-1 and Bfl-1. BOK expression is high during early placental development, suggesting that it may also play a role in regulating trophoblast cell proliferation.
PubMed ID:http://aac.asm.org/content/42/4/785.abstract
