Product Name: ATG14 Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, IF, WB
Applications: ATG14 antibody can be used for detection of ATG14 by Western blot at 1 – 2 μg/mL. For immunofluorescence start at 20 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 54 kDa
Immunogen: ATG14 antibody was raised against an 18 amino acid synthetic peptide near the center of human ATG14.The immunogen is located within amino acids 270 – 320 of ATG14.
Host Species: Rabbit
Purification: ATG14 Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 1393466-87-9
Product: PLX8394
Buffer: ATG14 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: ATG14 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: ATG14 Antibody: ATG14L, BARKOR, KIAA0831, Beclin 1-associated autophagy-related key regulator, Autophagy-related protein 14-like protein, Barkor
Accession NO.: NP_055739
Protein Ino: 50540545
Official Symbol: ATG14
Geneid: 22863
Background: ATG14 Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein ATG1. ATG14 is a subunit of a class III phosphatidylinositol (PtdIns) 3-kinase complex that targets the complex to the endoplasmic reticulum, the site of autophagosome formation.
PubMed ID:http://aac.asm.org/content/53/7/2791.abstract
