Product Name: ATF-2 (phospho Ser472) Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: IHC
Applications:
User Note:
Predicted Molecular Weight: 54 kDa
Immunogen: ATF-2 (phospho Ser472) antibody was raised against a peptide sequence around phosphorylation site of Serine 472 (E-A-V (p)-A-T) derived from Human ATF-2.
Host Species: Rabbit
Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Physical State: Liquid
CAS NO.: 1668553-26-1
Product: A-1210477
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Conditions: Store antibody at -20˚C for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Activating 2, ATF2, cAMP response element binding protein CRE- BP1, CREB2, HB16
Accession NO.: NP_001243019.1
Protein Ino: 22538422
Official Symbol: ATF2
Geneid: 1386
Background: Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5-GTGACGT[AC][AG]-3), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex.
PubMed ID:http://aac.asm.org/content/53/6/2579.abstract
