Product Name: ADORA2B Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, IF, IHC-P, WB
Applications: ADORA2B antibody can be used for detection of ADORA2B by Western blot at 0.25 – 0.5 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 37 kDa Observed: 41 kDa
Immunogen: ADORA2B antibody was raised against a 19 amino acid peptide near the carboxy terminus of human ADORA2B.The immunogen is located within the last 50 amino acids of ADORA2B.
Host Species: Rabbit
Purification: ADORA2B antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 6754-58-1
Product: Xanthohumol
Buffer: ADORA2B antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: ADORA2B antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Adenosine receptor A2b, ADORA2
Accession NO.: NP_000667
Protein Ino: 4501951
Official Symbol: ADORA2B
Geneid: 136
Background: The adenosine receptor ADORA2B is a member of the G protein-coupled receptor superfamily and is an integral membrane protein that stimulates adenylate cyclase activity in the presence of adenosine (1,2). Extracellular adenosine triggers a potent anti-inflammatory response that is mediated in part by ADORA2B including the stimulation of IL-10 production (3-5). Activation of ADORA2B can also enhance the abundance of regulatory T cells (Tregs), a class of cells that work to constrain inflammation (6).
PubMed ID:http://aac.asm.org/content/52/5/1663.abstract
