Product Name: Caspase 9 Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: Western Blot: 1:1000
User Note:
Predicted Molecular Weight: 47, 37, 35 kDa
Immunogen: Caspase 9 antibody was raised against a peptide sequence around aa.301~305 (T-S-P-E-D) derived from Caspase 9.
Host Species: Rabbit
Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Physical State: Liquid
CAS NO.: 1394076-92-6
Product: GNE-317
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Conditions: Store antibody at -20˚C for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: MCH6, APAF3, APAF-3, PPP1R56, ICE-LAP6, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1, ICE-like apoptotic protease 6
Accession NO.: NP_001220.2
Protein Ino: 14790124
Official Symbol: CASP9
Geneid: 842
Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
PubMed ID:http://aac.asm.org/content/43/5/1189.abstract
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Product Name: Caspase-9 Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, IP, WB
Applications: Caspase-9 antibody can be used for detection of caspase-9 by Western blot at 1:1000 dilution. A 46 kDa band should be detected.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 46 kDa
Immunogen: Caspase-9 antibody was raised against a 16 amino acid peptide near the amino terminus of human Caspase-9.The immunogen is located within amino acids 30 – 80 of Caspase-9.
Host Species: Rabbit
Purification: Caspase-9 Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 54197-31-8
Product: R(+)-IAA-94
Buffer: Caspase-9 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
Storage Conditions: Caspase-9 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Caspase-9 Antibody: MCH6, APAF3, APAF-3, PPP1R56, ICE-LAP6, MCH6, Caspase-9, Apoptotic protease Mch-6, CASP-9
Accession NO.: P55211
Protein Ino: 28558771
Official Symbol: CASP9
Geneid: 842
Background: Caspase-9 Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. A novel member in the caspase family was recently identified and designated ICE-LAP6, Mch6, and Apaf-3. Caspase-9 and Apaf-1 bind to each other, which leads to caspase-9 activation. Caspase-9 is also activated by granzyme B and CPP32. Activated caspase-9 cleaves and activates caspase-3 that is one of the key proteases, being responsible for the proteolytic cleavage of many key proteins in apoptosis. Caspase-9 play a central role in cell death induced by a wide variety of apoptosis activators including TNFα, TRAIL, anti-CD-95, FADD, and TRADD. Caspase-9 is expressed in a variety of human tissues.
PubMed ID:http://aac.asm.org/content/43/5/1301.abstract