Product Name: CD184 Antibody [2B11] (PE)
Species Reactivity: Mouse
Tested Applications: Flow
Applications:
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen:
Host Species: Rat
Purification: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Physical State: liquid
CAS NO.: 5852-78-8
Product: IOX1
Buffer: Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration: 0.2 mg/mL
Storage Conditions: The product should be stored undiluted at 4˚C and should be protected from prolonged exposure to light. Do not freeze.
Clonality: Monoclonal
Conjugate: PE
Alternate Names: CD184, LESTR, Sdf1r, Cmkar4, PB-CKR, b2b220Clo, PBSF/SDF-1
Accession NO.:
Protein Ino:
Official Symbol: Cxcr4
Geneid: 12767
Background: The 2B11 monoclonal antibody specifically reacts with mouse CD184 (CXCR4or Fusin), a seven-transmembrane G-protein-coupled receptor. It is expressed by astrocytes, B cells, T cells, monocytes, neutrophils, neurons, and hematopoietic cell types. CD184 is a coreceptor for X4 HIV-1.The monoclonal 2B11 antibody recognizes the amino terminus of CD184 and has functional activity.
PubMed ID:http://aac.asm.org/content/34/2/306.abstract
