Product Name: CD284 Antibody [HTA125] (PE)
Species Reactivity: Human
Tested Applications: Flow
Applications:
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen:
Host Species: Mouse
Purification: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Physical State: liquid
CAS NO.: 478336-92-4
Product: ISO-1
Buffer: Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration: 5 uL (2.0 ug) / test
Storage Conditions: The product should be stored undiluted at 4˚C and should be protected from prolonged exposure to light. Do not freeze.
Clonality: Monoclonal
Conjugate: PE
Alternate Names: TOLL, CD284, TLR-4, ARMD10, TLR4
Accession NO.:
Protein Ino:
Official Symbol: TLR4
Geneid: 7099
Background: The HTA125 monoclonal antibody specifically reacts with human CD284, a 110kDA type I transmembrane signaling molecule known as the Toll-like Receptor 4 (TLR4). CD284 is an important molecule in the innate immunity response to bacterial lipoproteins. It is expressed by monocytes, macrophages, and endothelial cells. The HTA125 antibody can block Lipopolysaccharide-induced cytokine production and immunoprecipitate human TLR4.
PubMed ID:http://aac.asm.org/content/34/6/954.abstract
