Product Name: cdc25C (Ab 216) Antibody
Species Reactivity: Human
Tested Applications: IF, IHC, WB
Applications: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
User Note:
Predicted Molecular Weight: 60 kDa
Immunogen: cdc25C (Ab-216) antibody was raised against a peptide sequence around aa.214~218 (S-P-S-M-P) derived from Human cdc25C.
Host Species: Rabbit
Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Physical State: Liquid
CAS NO.: 356-12-7
Product: Fluocinonide
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Conditions: Store antibody at -20˚C for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: CDC25, PPP1R60, CREB2, CREBP1, CDC25M1, MPIP3
Accession NO.: NP_001781.2
Protein Ino: 125625350
Official Symbol: CDC25C
Geneid: 995
Background: cdc25C is highly conserved during evolution and it plays a key role in the regulation of cell division. The encodedprotein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
PubMed ID:http://aac.asm.org/content/35/7/1376.abstract
