Product Name: IL-37 Antibody
Species Reactivity: Human
Tested Applications: ELISA, IHC, IP, WB
Applications: ELISA: (direct and indirect: 1:2,000-1:5,000), Immunohistochemistry: (1:50)Immunoprecipitation: (1:500- 1:2,000). Western Blot: (1:2,000-1:5,000 using ECL; suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk; suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: Recombinant human IL-37.
Host Species: Rabbit
Purification:
Physical State: Liquid
CAS NO.: 341-69-5
Product: Diosgenin
Buffer: Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration: 1 mg/ml
Storage Conditions: Stable for at least 6 months after receipt when stored at -20˚C.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Interleukin-1 Family Member 7; IL-1F7; FIL1 zeta; IL-1X; Interleukin-1 Homolog 4; IL-1H4; Interleukin-1 zeta; IL-1 zeta; IL-1RP1; IL1F7; FIL1Z, IL1H4, IL1RP1
Accession NO.: NP_055254
Protein Ino: 20127524
Official Symbol: IL37
Geneid: 27178
Background: IL-37 (Interleukin-37) belongs to the IL-1 family. It binds to interleukin-18 receptor (IL-18R) but not to IL-1 receptor. It was shown to play an important role as a link between innate and adaptive immunity and it is suggested as a new player in the inflammatory and immune responses mediated by the IL-18/IL-18R axis. It was also shown to inhibit tumor growth.
PubMed ID:http://aac.asm.org/content/26/4/485.abstract
