Product Name: IL-34 Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB
Applications: IL-34 antibody can be used for the detection of IL-34 by Western blot at 0.25 μg/mL. Despite its predicted molecular weight, IL-34 will often run at higher molecular weight in SDS-PAGE.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 26 kDa Observed: 42-48 kDa
Immunogen: IL-34 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human IL-34.The immunogen is located within amino acids 30 – 80 of IL-34.
Host Species: Rabbit
Purification: IL-34 Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 35554-44-0
Product: Ligustilide
Buffer: IL-34 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: IL-34 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: IL-34 Antibody: IL-34, C16orf77, Interleukin-34, IL-34
Accession NO.: ACD13474
Protein Ino: 187610438
Official Symbol: IL34
Geneid: 146433
Background: IL-34 Antibody: Interleukin-34 (IL-34) was identified through a functional screening of a library of secreted proteins after transfection of an embryonic kidney cell line with recombinant cDNAs. Flow cytometry and monocyte viability assays demonstrated increased survival and/or proliferation of monocytes induced by IL-34 and specific binding of IL-34 to CD14+ monocytes. IL-34 is a second ligand to the colony stimulating factor (CSF)-1 receptor in addition to CSF1. Like CSF1, IL-34 stimulates phosphorylation of ERK1 and ERK2 in human monocytes and induces differentiation of bone marrow cells into macrophages.
PubMed ID:http://aac.asm.org/content/26/4/455.abstract
