Product Name: HDAC3 Antibody
Species Reactivity: Human
Tested Applications: IHC-P, WB
Applications: For WB starting dilution is: 1:1000For IHC-P starting dilution is: 1:10~50
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 49 kDa
Immunogen: This HDAC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 383-412 amino acids from the C-terminal region of human HDAC3.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 1808011-22-4
Product: Vps34-PIK-III
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Histone deacetylase 3, HD3, RPD3-2, SMAP45, HDAC3
Accession NO.: O15379
Protein Ino:
Official Symbol: HDAC3
Geneid: 8841
Background: Histones play a critical role in transcriptionalregulation, cell cycle progression, and developmental events.Histone acetylation/deacetylation alters chromosome structure andaffects transcription factor access to DNA. The protein encoded bythis gene belongs to the histone deacetylase/acuc/apha family. Ithas histone deacetylase activity and represses transcription whentethered to a promoter. It may participate in the regulation oftranscription through its binding with the zinc-fingertranscription factor YY1. This protein can also down-regulate p53function and thus modulate cell growth and apoptosis. This gene isregarded as a potential tumor suppressor gene. [provided byRefSeq].
PubMed ID:http://aac.asm.org/content/21/4/622.abstract
