Product Name: HADHSC Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB
Applications: Short chain 3-hydroxyacyl-CoA dehydrogenase, mitochondrial antibody can be used for the detection of Short chain 3-hydroxyacyl-CoA dehydrogenase, mitochondrial by Western Blot.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 34.3 kDa (calculated)
Immunogen: 57-314
Host Species: Chicken
Purification: Immunoaffinity Purified
Physical State: Liquid
CAS NO.: 16009-13-5
JTC-801
Buffer: Phosphate-Buffered Saline. No preservatives added.
Concentration: 1 mg/mL
Storage Conditions: HADHSC antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: HAD, HADHSC, SCHAD, Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial, Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase, HCDH, Short chain 3hydroxyacylCoA dehydrogenase, Medium and short chain L-3-hydroxyacyl-coenzyme A dehydrogenase
Accession NO.: NP_005318.1
Protein Ino: 4885387
Official Symbol: HADH
Geneid: 3033
Background: FUNCTION: Plays an essential role in the mitochondrial β-oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA.DISEASE: Defects in HADHSC are the cause of 3-α-hydroxyacyl-CoA dehydrogenase deficiency (HAD deficiency) [MIM:609609]. HAD deficiency is a metabolic disorder with various clinical presentations including hypoglycemia, hepatoencephalopathy, myopathy or cardiomyopathy, and in some cases sudden death.
PubMed ID:http://aac.asm.org/content/21/1/151.abstract
