Product Name: GUCY2C Antibody
Species Reactivity: Bovine, Chicken, Human
Tested Applications: WB
Applications: Heat-stable enterotoxin receptor antibody can be used for the detection of Heat-stable enterotoxin receptor by Western Blot.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 123.4 kDa (calculated)
Immunogen: 971-1073
Host Species: Chicken
Purification: Immunoaffinity Purified
Physical State: Liquid
CAS NO.: 1008763-54-9
Cebranopadol
Buffer: Phosphate-Buffered Saline. No preservatives added.
Concentration: 1 mg/mL
Storage Conditions: GUCY2C antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: GUC2C, STAR, Heat-stable enterotoxin receptor, Guanylyl cyclase C, STA receptor, Heatstable enterotoxin receptor, GC-C, Intestinal guanylate cyclase, hSTAR
Accession NO.: NP_004954.1
Protein Ino: 4826752
Official Symbol: GUCY2C
Geneid: 2984
Background: FUNCTION: Receptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptide guanylin.CATALYTIC ACTIVITY: GTP = 3,5-cyclic GMP + diphosphate.SUBUNIT: Interacts via its C-terminal region with PDZK2.SIMILARITY: Contains 1 protein kinase-like domain.SUBCELLULAR LOCATION: Membrane; single-pass type I membrane protein.
PubMed ID:http://aac.asm.org/content/20/6/800.abstract
