Product Name: GPX3 Antibody (biotin)
Species Reactivity: Mouse
Tested Applications: ELISA, WB
Applications: ELISA: (direct and indirect: 1:2,000-1:5,000). Western Blot: (1:2,000-1:5,000 using ECL; suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk; suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: Recombinant mouse GPX3.
Host Species: Rabbit
Purification:
Physical State: Liquid
CAS NO.: 638132-34-0
SP2509
Buffer: Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration: 1 mg/ml
Storage Conditions: Stable for at least 6 months after receipt when stored at -20˚C.
Clonality: Polyclonal
Conjugate: Biotin
Alternate Names: Glutathione Peroxidase 3
Accession NO.: P46412
Protein Ino: 172046853
Official Symbol: Gpx3
Geneid: 14778
Background: Glutathione peroxidase 3 (GPX3; GSHPX3) is a selenium-dependent extracellular enzyme, protecting cells and enzymes from oxidative damage by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxides. GPX3 is involved in inflammatory bowel disease, in asthma and in diabetes. The activity of GPX3 is significantly reduced in the plasma and tissue of cancer patients. Recently, GPX3 was suggested to serve as a molecular marker for the diagnosis of clear cell type ovarian adenocarcinoma.
PubMed ID:http://aac.asm.org/content/19/5/891.abstract
