Product Name: GCAT Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 45 kDa
Immunogen: This GCAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101-128 amino acids from the N-terminal region of human GCAT.
Host Species: Rabbit
Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Physical State: Liquid
CAS NO.: 1431280-51-1
product targets : CMV inhibitors
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 2 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial, AKB ligase, Aminoacetone synthase, Glycine acetyltransferase, GCAT, KBL
Accession NO.: O75600
Protein Ino:
Official Symbol: GCAT
Geneid: 23464
Background: The degradation of L-threonine to glycine consists of atwo-step biochemical pathway involving the enzymes L-threoninedehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase.L-Threonine is first converted into 2-amino-3-ketobutyrate byL-threonine dehydrogenase. This gene encodes the second enzyme inthis pathway, which then catalyzes the reaction between2-amino-3-ketobutyrate and coenzyme A to form glycine andacetyl-CoA. The encoded enzyme is considered a class IIpyridoxal-phosphate-dependent aminotransferase. Alternate splicingresults in multiple transcript variants. A pseudogene of this geneis found on chromosome 14.
PubMed ID:http://aac.asm.org/content/17/3/322.abstract
