Product Name: FREM1 Antibody
Species Reactivity: Human, Mouse
Tested Applications: ELISA, ICC, IF, WB
Applications: FREM1 antibody can be used for detection of FREM1 by Western blot at 0.5 – 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 20 μg/mL. For immunofluorescence start at 20 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: FREM1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human FREM1.The immunogen is located within the last 50 amino acids of FREM1.
Host Species: Rabbit
Purification: FREM1 Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 187389-52-2
product targets : CFTR inhibitors
Buffer: FREM1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: FREM1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: FREM1 Antibody: BNAR, MOTA, TILRR, TRIGNO2, C9orf143, C9orf145, C9orf154, FRAS1-related extracellular matrix protein 1, Protein QBRICK
Accession NO.: NP_659403
Protein Ino: 122056683
Official Symbol: FREM1
Geneid: 158326
Background: FREM1 Antibody: FREM1 is a member of the FRAS1-related extracellular matrix protein family and is thought to play a role in craniofacial and renal development. FREM1 functions as an extracellular matrix protein that is essential for epidermal adhesion during embryogenesis and may also participate in epidermal differentiation. It is recognized by cells in the embryonic skin and hair follicles through different members of the integrin family. Deficiency in the Fras1/Frem genes gives rise to the bleb phenotype, which is equivalent to the human hereditary disorder Fraser syndrome.
PubMed ID:http://aac.asm.org/content/41/7/1566.abstract
