Product Name: FEZ2 Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, IF, WB
Applications: FEZ2 antibody can be used for the detection of FEZ2 by Western blot at 0.5 – 1 μg/mL. Antibody can also be used for immunoflourescence starting at 5 μg/mL. For immunofluorescence start at 5 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: FEZ2 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human FEZ2.The immunogen is located within the last 50 amino acids of FEZ2.
Host Species: Rabbit
Purification: FEZ2 Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 932730-51-3
CDDO-EA
Buffer: FEZ2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: FEZ2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: FEZ2 Antibody: HUM3CL, Fasciculation and elongation protein zeta-2, Zygin II
Accession NO.: NP_001036013
Protein Ino: 110349756
Official Symbol: FEZ2
Geneid: 9637
Background: FEZ2 Antibody: Fasciculation and elongation protein zeta-2 (FEZ2) is a homolog to the mammalian FEZ1, itself an ortholog of the C. elegans UNC-76. In contrast to FEZ1, FEZ2 mRNA is widely expressed in mouse tissues. FEZ2 interacts with protein kinase C (PKC)-zeta substrate and induces neurite extension of PC12 cells when co-expressed with a constitutively active form of PKC-zeta, suggesting FEZ2 may play an important role in the morphological changes of various cells by associating with PKC-zeta in a tissue non-specific manner. FEZ2 can interact with FEZ1 through its c-terminal regions and especially its coiled-coil region. At least two isoforms of FEZ2 are known to exist.
PubMed ID:http://aac.asm.org/content/40/12/2714.abstract
