Product Name: EphA1 Antibody [5D2A4 / 5D2A10]
Species Reactivity: Human
Tested Applications: IHC, WB
Applications: Western Blot:1:500 – 1:2,000IHC(P):1:500 – 1:2,000IHC(F):1:500 – 1:2,000ELISA:Propose dilution 1:10,000.Determining optimal working dilutions by titration test.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: Ni-NTA purified truncated recombinant EphA1 expressed in E. Coli strain BL21 (DE3).
Host Species: Mouse
Purification: Antibody is purified by protein A affinity chromatography.
Physical State:
CAS NO.: 794466-70-9
Product: Vernakalant
Buffer: Purified antibody in PBS containing 0.03% sodium azide.
Concentration:
Storage Conditions: EphA1 monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Monoclonal
Conjugate: Unconjugated
Alternate Names: EPH, EPHT, EPHT1
Accession NO.: NP_005223.4
Protein Ino: 221316650
Official Symbol: EPHA1
Geneid: 2041
Background: EPH receptor A1 (EphA1), with 976-amino acid protein(about 107 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date and their ligands, the ephrins,can be subdivided into two major subclasses, ephrin-A and ephrin-B. Interaction of Eph receptor tyrosine kinases with their membrane bound ephrin ligands initiates bidirectional signaling events that regulate cell migratory and adhesive behavior, particularly in the nervous system. They have been implicated in various developmental processes, including axonal guidance, angiogenesis, morphogenesis and carcinogenesis.
PubMed ID:http://aac.asm.org/content/39/12/2749.abstract
