Product Name: ERCC8 Antibody
Species Reactivity: Human
Tested Applications: ELISA, WB
Applications: ERCC8 antibody can be used for detection of ERCC8 by ELISA at 1:62500. ERCC8 antibody can be used for detection of ERCC8 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 44 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ERCC8.
Host Species: Rabbit
Purification: Antibody is purified by peptide affinity chromatography method.
Physical State: Lyophilized
CAS NO.: 331771-20-1
Product: ZM-447439
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store ERCC8 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: ERCC8, CKN1, CSA, UVSS2
Accession NO.: NP_000073
Protein Ino: 4557467
Official Symbol: ERCC8
Geneid: 1161
Background: ERCC8 is a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS).This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes.
PubMed ID:http://aac.asm.org/content/40/2/314.abstract
