Product Name: ENSA Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB
Applications: ENSA antibody can be used for the detection of ENSA by Western blot, may also work for IHC and ICC.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 13.4 kDa (calculated)
Immunogen: 1-121
Host Species: Chicken
Purification: Antigen affinity-purified
Physical State: Liquid
CAS NO.: 501919-59-1
Product: NSC 74859
Buffer: Phosphate-Buffered Saline. No preservatives added.
Concentration: 1 mg/mL
Storage Conditions: ENSA antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Alpha-endosulfine, ARPP-19e,
Accession NO.: NP_004427.1
Protein Ino: 4758272
Official Symbol: ENSA
Geneid: 2029
Background: Endosulfine α. α-endosulfine is expressed in a wide range of tissues including muscle, brain, and endocrine tissues. The recombinant protein inhibits binding of labeled glibenclamide to β cell membranes. It also inhibits cloned K(ATP) channel currents and thereby stimulates insulin secretion. It was proposed that endosulfine is an endogenous regulator of the K(ATP) channel, which has a key role in the control of insulin release and, more generally, couples cell metabolism to electrical activity.
PubMed ID:http://aac.asm.org/content/39/11/2436.abstract
