Product Name: Deoxycytidine Kinase Antibody
Species Reactivity: Human
Tested Applications: ELISA, IHC, WB
Applications: Deoxycytidine Kinase antibody can be used in Western Blot starting at 0.5 – 2 μg/mL, and immunohistochemistry starting at 10 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: Deoxycytidine Kinase antibody was raised against a synthetic peptide corresponding to N-Terminal residues of Deoxycytidine Kinase (Human).
Host Species: Rabbit
Purification: Immunoaffinity Chromatography
Physical State: Liquid
CAS NO.: 56396-35-1
Product: UK-5099
Buffer: PBS, 0.01% sodium azide, 50% glycerol.
Concentration:
Storage Conditions: Store Deoxycytidine Kinase antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: DCK, Deoxynucleoside kinase, Deoxycytidine kinase
Accession NO.: P27707
Protein Ino: 118447
Official Symbol: DCK
Geneid: 1633
Background: De oxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.
PubMed ID:http://aac.asm.org/content/38/6/1251.abstract
