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Product Name: CD51/CD61 Antibody [23C6]
Species Reactivity: Human
Tested Applications: Flow, Func
Applications:
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen:
Host Species: Mouse
Purification: The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Physical State: liquid
CAS NO.: 74397-12-9
Product: Limaprost
Buffer: Phosphate-buffered aqueous solution, ph7.2.
Concentration: 1 mg/mL
Storage Conditions: The product should be stored undiluted at 4˚C . Do not freeze.
Clonality: Monoclonal
Conjugate: Unconjugated
Alternate Names: CD51, MSK8, VNRA, VTNR, GT, CD61, GP3A, BDPLT2, GPIIIa, BDPLT16, ITGAV, ITGB3
Accession NO.:
Protein Ino:
Official Symbol: ITGAV; ITGB3
Geneid: 3685; 3690
Background: The 23C6 monoclonal antibody specifically reacts with the human CD51/61 molecule, known as the integrin alpha v Beta 3 complex or vitronectin receptor. The complex binds to other ligands such as CD29, fibrinogen, fibrinectin, vWf, laminin, and thrombospondin. It is expressed by endothelial cells, osteoclasts, melanoma cells, and at low levels on platelets and macrophages. The 23C6 antibody is reported to be able to block the receptors ability to form interactions with some of its ligands.
PubMed ID:http://aac.asm.org/content/35/1/62.abstract

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Author: Betaine hydrochloride