Product Name: IL-8 Receptor B Antibody, Monoclonal
Species Reactivity: Human
Tested Applications: Flow, IHC
Applications: IL-8 Receptor B antibody can be used in immunohistochemistry starting at 5 μg/mL, immunohistochemistry in frozen tissues starting at 1:10 – 1:20, and flow cytometry.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: IL – 8 Receptor B monoclonal antibody was raised against L1.2 cells expressing IL – 8 Receptor B (Human).
Host Species: Mouse
Purification: Protein G Column
Physical State: Liquid
CAS NO.: 3383-96-8
Product: TP-10
Buffer: PBS.
Concentration: 1 mg/mL
Storage Conditions: Store IL-8 Receptor B antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
Clonality: Monoclonal
Conjugate: Unconjugated
Alternate Names: CXCR2, CDw128b, CD182 antigen, CMKAR2, CXCR-2, CD182, CXC-R2, IL-8R B, Il-8 receptor b, IL-8 receptor type 2, Il-8rb, IL8R2, IL8RB, Interleukin-8 receptor type B, GRO/MGSA receptor, Interleukin 8 receptor beta, Interleukin 8 receptor, beta, Chemokine (CXC) receptor 2, IL8RA, Interleukin 8 receptor B, Interleukin 8 receptor type 2
Accession NO.: P25025
Protein Ino: 1352454
Official Symbol: CXCR2
Geneid: 3579
Background: Flow Cytometry Recognizes human IL-8 receptor, type B.The IL8RB is a Chemokine Receptor also known as type 1 interleukin-8 receptor. There are three interleukin-8 receptors on chromosome 2: IL8RA (type 2), IL8RB (type 1), and a pseudogene. Results from mouse knock-out studies suggest that IL8RB may inhibit the expansion and development of neutrophils and B cells (Cacalano et al., 1994). IL8RB is a high-affinity receptor for IL8, and for GROalpha, beta, and gamma (Ahuja and Murphy, 1996).
PubMed ID:http://aac.asm.org/content/26/5/643.abstract
