igure 4). Most annotated genes within the biological processes category had been associated to the inflammatory response and cellular metabolism. DEGs in comparison group S_Z vs. S_B have been mainly linked to GO terms associated to stimulation, biological processes connected with lipid synthesis, and metabolism, including the lipid/organic substance catabolic approach as well as the inflammatory/stimulus response. The majority of DEGs in comparison group K_Z vs. K_B had been connected with stimulationrelated biological processes, G-protein coupled receptor activity, signal transduction-related molecular functions, and cellular elements (cytoskeletal element, membrane element, p70S6K site cytoplasm), like the acute-phase response, G protein-coupled peptide receptor activity, and transmembrane transporter activity. The majority of DEGs in comparison group H_Z vs. H_B have been assigned with biological processes connected with stimulus, cellular processes, and cellular elements, like cellular response to endogenous stimulus, unfavorable regulation of biological process, regulation of major metabolic process, and positive regulation of biological approach. The majority of DEGs in comparison group M_Z vs. M_B had been related to stimulus, immune procedure, cellular processes, signal transductionrelated molecular functions, and cellular elements, for Nav1.4 Molecular Weight example response to abiotic stimulus,Animals 2021, 11,9 ofpositive regulation of neutrophil migration, cellular response to interleukin-1, positive regulation of biological method, and intracellular signal transduction. The majority of DEGs in comparison group J_Z vs. J_B have been associated with stimulus, immune process, G protein-coupled peptide receptor activity, cellular procedure, and cellular components, for example cellular response to chemical stimulus, G protein-coupled receptor signaling pathway, cellular response to interleukin-1, neutrophil chemotaxis, constructive regulation of cellular process, and cell migration. The majority of DEGs in comparison group Z_Z vs. Z_B were related to cell development, tissue improvement, cellular process, and cellular elements, which include striated muscle tissue development, striated muscle cell development, muscle structure improvement, and cell differentiation. In addition, the evaluation identified 9, 21, 25, five, 12, and 1 KEGG pathways that have been drastically enriched in DEGs in comparison groups S_Z vs. S_B, K_Z vs. K_B, H_Z vs. H_B, M_Z vs. M_B, J_Z vs. J_B, and Z_Z vs. Z_B, respectively (Figure five). The considerably enriched pathways in DEGs from comparison group S_Z vs. S_B primarily included the complement and coagulation cascades and protein digestion and absorption (Figure 6). The pathways considerably enriched in DEGs from comparison group K_Z vs. K_B primarily incorporated complement and coagulation cascades, IL-17 signaling pathway, and PI3K-Akt signaling pathway. The drastically enriched pathways in DEGs from comparison group H_Z vs. H_B primarily included the complement and coagulation cascades, protein digestion and absorption, PI3K-Akt signaling pathway, MAPK signaling pathway, and NF-kappa B signaling pathway. The pathways that had been considerably enriched inside the DEGs from comparison group M_Z vs. M_B primarily integrated protein digestion and absorption, IL17 signaling pathway, TNF signaling pathway, NF-kappa B signaling pathway, NODlike receptor signaling pathway, and HIF-1 signaling pathway. The pathways that were substantially enriched inside the DEGs from comparison group J_Z vs. J_B mostly included
