Product Name: EGF Receptor Antibody
Species Reactivity: Gorilla, Human
Tested Applications: IHC
Applications: EGF Receptor antibody can be used in immunohistochemistry starting at 1:50.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: EGF Receptor antibody was raised against a peptide located in the C-Terminal domain of EGF Receptor (Human).
Host Species: Rabbit
Purification: Immunoaffinity Chromatography
Physical State: Liquid
CAS NO.: 50-07-7
Product: Mitomycin C
Buffer: PBS, 0.1% sodium azide.
Concentration:
Storage Conditions: EGF Receptor antibody should be stored long term (months) at -80 ˚C and short term (days) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: EGFR, EGFf receptor, ERBB, ERBB1, MENA, Panitumumab, PIG61, Proto-oncogene c-ErbB-1, V-erb-b homolog, EGF-R, HER1
Accession NO.: P00533
Protein Ino: 2811086
Official Symbol: EGFR
Geneid: 1956
Background: Epidermal growth factor receptor (EGFR) is a tyrosine protein kinase comprised of two different components of different molecular weights. Both components contain phosphotyrosine and phosphothreonine but only the higher molecular weight component contains phosphoserine. EGFR signaling involves small GTPases of the Rho family and EGFR trafficking involves small GTPases of the Rab family. EGFR expression is widespread in both normal and cancerous tissues.
PubMed ID:http://aac.asm.org/content/39/6/1265.abstract
