Product Name: CAV3 Antibody
Species Reactivity: Dog, Human
Tested Applications: ELISA, WB
Applications: CAV3 antibody can be used for detection of CAV3 by ELISA at 1:12500. CAV3 antibody can be used for detection of CAV3 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 17 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CAV3.
Host Species: Rabbit
Purification: Antibody is purified by peptide affinity chromatography method.
Physical State: Lyophilized
CAS NO.: 19879-30-2
Product: Bavachinin
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store CAV3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: CAV3, LQT9, VIP21, LGMD1C, VIP-21
Accession NO.: NP_001225
Protein Ino: 4502589
Official Symbol: CAV3
Geneid: 859
Background: CAV3 is a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.
PubMed ID:http://aac.asm.org/content/43/6/1362.abstract
