Product Name: GNLY Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 16 kDa
Immunogen: This GNLY antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-42 amino acids from the N-terminal region of human GNLY.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 1025967-78-5
CX-5461
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Granulysin, Lymphokine LAG-2, Protein NKG5, T-cell activation protein 519, GNLY, LAG2, NKG5, TLA519
Accession NO.: P22749
Protein Ino: 116242500
Official Symbol: GNLY
Geneid: 10578
Background: The product of this gene is a member of the saposin-likeprotein (SAPLIP) family and is located in the cytotoxic granules ofT cells, which are released upon antigen stimulation. This proteinis present in cytotoxic granules of cytotoxic T lymphocytes andnatural killer cells, and it has antimicrobial activity against M.tuberculosis and other organisms. Alternatively spliced transcriptvariants encoding different isoforms have been identified.
PubMed ID:http://aac.asm.org/content/19/1/29.abstract
