Product Name: GLIS3 Antibody
Species Reactivity: Dog, Human
Tested Applications: ELISA, WB
Applications: GLIS3 antibody can be used for detection of GLIS3 by ELISA at 1:62500. GLIS3 antibody can be used for detection of GLIS3 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 84 kDa, 100 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GLIS3.
Host Species: Rabbit
Purification: Antibody is purified by protein A chromatography method.
Physical State: Lyophilized
CAS NO.: 40077-57-4
SLx-2119
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store GLIS3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: GLIS3, ZNF515
Accession NO.: NP_689842
Protein Ino: 109637782
Official Symbol: GLIS3
Geneid: 169792
Background: GLIS3 is a member of the GLI-similar zinc finger protein family and has five C2H2-type zinc finger domains. GLIS3 functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH).
PubMed ID:http://aac.asm.org/content/18/2/338.abstract
