Product Name: EGFR (phospho Tyr1172) Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: IHC, WB
Applications: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
User Note:
Predicted Molecular Weight: 175 kDa
Immunogen: EGFR (Phospho-Tyr1172) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 1172 (P-D-Y (p) -Q-Q) derived from Human EGFR.
Host Species: Rabbit
Purification: Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Physical State: Liquid
CAS NO.: 156053-89-3
Product: Alvimopan
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Conditions: Store antibody at -20˚C for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: ERBB, HER1, mENA, ERBB1, PIG61, NBS, NBS1, P95, Receptor protein-tyrosine kinase ErbB-1, kinase EGFR
Accession NO.: NP_005219.2
Protein Ino: 29725609
Official Symbol: EGFR
Geneid: 1956
Background: Receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with SRC and CTNNB1/beta-catenin.
PubMed ID:http://aac.asm.org/content/39/6/1369.abstract
