Product Name: DENR Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, IF, IHC-P, WB
Applications: DENR antibody can be used for detection of DENR by Western blot at 1 – 2 μg/ml. Antibody can also be used for Immunohistochemistry at 5 μg/mL. For Immunoflorescence start at 20 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 22 kDa Observed: 22 kDa
Immunogen: DENR antibody was raised against an 18 amino acid peptide near the center of human DENR.The immunogen is located within amino acids 80 – 130 of DENR.
Host Species: Rabbit
Purification: DENR antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 2114454
Product: Campathecin
Buffer: DENR Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: DENR antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: DENR Antibody: DRP, DRP1, SMAP-3, H14, Density-regulated protein, Protein DRP1, DRP
Accession NO.: NP_003668
Protein Ino: 27501446
Official Symbol: DENR
Geneid: 8562
Background: DENR (density-regulated protein), also designated DRP or smooth muscle cell associated protein 3 (SMAP-3), is a 198 amino acid protein that may be involved in the translation of target mRNAs by scanning and recognition of the initiation codon (1). It plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1 (2,3). DENR contains a SUI1 domain and is found in a variety of tissues with highest levels present in skeletal and cardiac muscle. It is up-regulated in ovarian and breast cancer cells by ERBB2 overexpression (4).
PubMed ID:http://aac.asm.org/content/38/6/1246.abstract
