Product Name: CYTH4 Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 46 kDa
Immunogen: This CYTH4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-319 amino acids from the C-terminal region of human CYTH4.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 1492-18-8
Product: Folinic acid (Calcium)
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.28 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Cytohesin-4, PH, SEC7 and coiled-coil domain-containing protein 4, CYTH4, CYT4, PSCD4
Accession NO.: Q9UIA0
Protein Ino: 13124094
Official Symbol: CYTH4
Geneid: 27128
Background: The protein encoded by this gene is a member of the PSCDfamily. Members of this family have identical structuralorganization that consists of an N-terminal coiled-coil motif, acentral Sec7 domain, and a C-terminal pleckstrin homology (PH)domain. The coiled-coil motif is involved in homodimerization, theSec7 domain contains guanine-nucleotide exchange protein (GEP)activity, and the PH domain interacts with phospholipids and isresponsible for association of PSCDs with membranes. Members ofthis family appear to mediate the regulation of protein sorting andmembrane trafficking. The encoded protein exhibits GEP activity invitro with both ARF1 and ARF5 but is inactive with ARF6. Thestructures of this gene and CYTH1 are very similar. [provided byRefSeq].
PubMed ID:http://aac.asm.org/content/37/11/2506.abstract
