Product Name: CKit Antibody [8D7B4 / 8D7D4 / 7H6B2 / 7H6B12]
Species Reactivity: Human
Tested Applications: ELISA
Applications: DilutionELISA:Propose dilution 1:10,000Determining optimal working dilutions by titration test.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: Ni-NTA purified truncated recombinant C-kit expressed in E. Coli strain BL21 (DE3).
Host Species: Mouse
Purification: Antibody is purified by protein A affinity chromatography.
Physical State:
CAS NO.: 75695-93-1
Product: Isradipine
Buffer:
Concentration:
Storage Conditions: C-Kit monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Monoclonal
Conjugate: Unconjugated
Alternate Names: SCFR, Piebald trait protein, SCFR, PBT, C-Kit, CD117
Accession NO.: P10721
Protein Ino: 125472
Official Symbol: KIT
Geneid: 3815
Background: C-kit (CD117,145 kDa) functions as a tyrosine kinase receptor which becomes activated upon binding of its ligand SCF (stem-cell factor), the C-kit gene encodes the human homolog of the proto-oncogene c-kit. which was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor). Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.
PubMed ID:http://aac.asm.org/content/36/4/854.abstract
