Product Name: CD3 Antibody [Hit3a]
Species Reactivity: Human
Tested Applications: Flow, Func, IHC, IP
Applications:
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen:
Host Species: Mouse
Purification: The monoclonal antibody was purified utilizing affinity chromatography.
Physical State: liquid
CAS NO.: 859498-05-8
Product: AGN 205728
Buffer: Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration: 0.5 mg/mL
Storage Conditions: The product should be stored undiluted at 4˚C . Do not freeze.
Clonality: Monoclonal
Conjugate: Unconjugated
Alternate Names: T3E, TCRE, IMD18, CD3E
Accession NO.:
Protein Ino:
Official Symbol: CD3E
Geneid: 916
Background: The Hit3a monoclonal antibody specifically reacts with the epsilon chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction.The HIT3a antibody cross-links with the TCR complex, initiating the cellular activation and proliferation, but it cannot be used for intracellular CD3 staining, as it is able to stain only the surface CD3 complex.
PubMed ID:http://aac.asm.org/content/34/6/1048.abstract