Product Name: BTLA Antibody
Species Reactivity: Human
Tested Applications: ELISA, IF, IHC-P, WB
Applications: BTLA antibody can be used for detection of BTLA by Western blot at 1 – 2 μg/ml.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 32 kDa Observed: 40kDa
Immunogen: BTLA antibody was raised against a 17 amino acid peptide near the center of human BTLA.The immunogen is located within amino acids 170 – 220 of BTLA .
Host Species: Rabbit
Purification: BTLA Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 1225-55-4
Product: Protriptyline (hydrochloride)
Buffer: BTLA Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: BTLA antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: BTLA Antibody : BTLA1, CD272, B- and T-lymphocyte attenuator, B- and T-lymphocyte-associated protein
Accession NO.: NP_861445
Protein Ino: 145580621
Official Symbol: BTLA
Geneid: 151888
Background: The B- and T-lymphocyte attenuator (BTLA) protein is a member of the immunoglobulin superfamily containing a single immunoglobulin (Ig) domain (1). Like other coihibitory receptors such as CTLA-4 and PD-1, BTLA functions as a receptor that relays inhibitory signals to suppress the immune response, and can inhibit LPS-induced endotoxic shock by suppressing TLR4 signaling in innate immune cells (1,2). Polymorphisms in this gene have also been associated with an increased risk of rheumatoid arthritis (3).
PubMed ID:http://aac.asm.org/content/42/6/1517.abstract
