Product Name: AKR1C2 Antibody
Species Reactivity: Human
Tested Applications: IHC-P, WB
Applications: For WB starting dilution is: 1:1000For IHC-P starting dilution is: 1:10~50
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 37 kDa
Immunogen: This AKR1C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-323 amino acids from the C-terminal region of human AKR1C2.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 1011850
Product: Theaflavin
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.45 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Aldo-keto reductase family 1 member C2, 1—, 3-alpha-HSD3, Chlordecone reductase homolog HAKRD, Dihydrodiol dehydrogenase 2, DD-2, DD2, Dihydrodiol dehydrogenase/bile acid-binding protein, DD/BABP, Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase, Type III 3-alpha-hydroxysteroid dehydrogenase, AKR1C2, DDH2
Accession NO.: P52895
Protein Ino: 20532374
Official Symbol: AKR1C2
Geneid: 1646
Background: This gene encodes a member of the aldo/keto reductasesuperfamily, which consists of more than 40 known enzymes andproteins. These enzymes catalyze the conversion of aldehydes andketones to their corresponding alcohols using NADH and/or NADPH ascofactors. The enzymes display overlapping but distinct substratespecificity. This enzyme binds bile acid with high affinity, andshows minimal 3-alpha-hydroxysteroid dehydrogenase activity. Thisgene shares high sequence identity with three other gene membersand is clustered with those three genes at chromosome 10p15-p14.
PubMed ID:http://aac.asm.org/content/52/7/2367.abstract
