IL17B Antibody

Product Name: IL17B Antibody
Species Reactivity: Human, Mouse
Tested Applications: IF, IHC-P, WB
Applications: For WB starting dilution is: 1:1000For IHC-P starting dilution is: 1:10~50For IF starting dilution is: 1:10~50
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 20 kDa
Immunogen: This IL17B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-66 amino acids from the Central region of human IL17B.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 304-84-7
Product: TGR-1202
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.43 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Interleukin-17B, IL-17B, Cytokine Zcyto7, Interleukin-20, IL-20, Neuronal interleukin-17-related factor, IL17B, IL20, NIRF, ZCYTO7
Accession NO.: Q9UHF5
Protein Ino: 20143877
Official Symbol: IL17B
Geneid: 27190
Background: The protein encoded by this gene is a T cell-derivedcytokine that shares sequence similarity with IL17. This cytokinewas reported to stimulate the release of TNF alpha (TNF) and IL1beta (IL1B) from a monocytic cell line. Immunohistochemicalanalysis of several nerve tissues indicated that this cytokine isprimarily localized to neuronal cell bodies.
PubMed ID:http://aac.asm.org/content/26/5/707.abstract


IL17A Antibody

Product Name: IL17A Antibody
Species Reactivity: Human
Tested Applications: ELISA, WB
Applications: ELISA: antibody detection limit dilution 1:64000. Western Blot: Approx 19kDa band observed in HumanThymus lysates (calculated MW of 17.5kDa according to NP_002181.1). Recommended concentration: 1-3μg/ml.
User Note:
Predicted Molecular Weight: Approx 19 kDa
Immunogen: IL17A antibody was raised against a 15 amino acid peptide near the internal region of IL17A.
Host Species: Goat
Purification: IL17A antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Physical State: Liquid
CAS NO.: 306-20-7
Product: TGR-1202 (hydrochloride)
Buffer: IL17A antibody is supplied in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin.
Concentration: 500 ug/mL
Storage Conditions: Aliquot and store at -20˚C. Minimize freezing and thawing.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: CTLA8, CTLA-8, cytotoxic T-lymphocyte-associated antigen 8, cytotoxic T-lymphocyte-associated protein 8, cytotoxic T-lymphocyte-associated serine esterase 8, IL17, IL-17, IL17A, IL-17A, interleukin 17 (cytotoxic T-lymp, interleukin 17A, OTTHUMP00000016597 , CTLA8
Accession NO.: NP_002181.1
Protein Ino: 4504651
Official Symbol: IL17A
Geneid: 3605
Background:
PubMed ID:http://aac.asm.org/content/26/5/702.abstract


IL15 Antibody

Product Name: IL15 Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB
Applications: IL15 antibody can be used for detection of IL15 by ELISA at 1:312500. IL15 antibody can be used for detection of IL15 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 13 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IL15.
Host Species: Rabbit
Purification: Antibody is purified by peptide affinity chromatography method.
Physical State: Lyophilized
CAS NO.: 103-86-6
Product: Mavoglurant
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store IL15 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: IL15, IL-15, MGC9721
Accession NO.: NP_751914
Protein Ino: 26787984
Official Symbol: IL15
Geneid: 3600
Background: IL15 is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each others activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x (L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis.The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each others activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x (L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.
PubMed ID:http://aac.asm.org/content/26/5/699.abstract


IL13RA2 Antibody

Product Name: IL13RA2 Antibody
Species Reactivity: Dog, Human
Tested Applications: ELISA, WB
Applications: IL13RA2 antibody can be used for detection of IL13RA2 by ELISA at 1:312500. IL13RA2 antibody can be used for detection of IL13RA2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 22 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IL13RA2.
Host Species: Rabbit
Purification: Antibody is purified by peptide affinity chromatography method.
Physical State: Lyophilized
CAS NO.: 313-06-4
Product: Rocaglamide
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store IL13RA2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: IL13RA2, CD213A2, IL-13R, IL13BP, CT19
Accession NO.: EAX0262
Protein Ino: 2494720
Official Symbol: IL13RA2
Geneid: 3598
Background: IL13RA2 is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13.
PubMed ID:http://aac.asm.org/content/26/5/694.abstract


IL13RA1 Antibody

Product Name: IL13RA1 Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 49 kDa
Immunogen: This IL13RA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-85 amino acids from the N-terminal region of human IL13RA1.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 314-03-4
Product: CO-1686 (hydrobromide)
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Interleukin-13 receptor subunit alpha-1, IL-13 receptor subunit alpha-1, IL-13R subunit alpha-1, IL-13R-alpha-1, IL-13RA1, Cancer/testis antigen 19, CT19, CD213a1, IL13RA1, IL13R, IL13RA
Accession NO.: P78552
Protein Ino: 2494718
Official Symbol: IL13RA1
Geneid: 3597
Background: The protein encoded by this gene is a subunit of theinterleukin 13 receptor. This subunit forms a receptor complex withIL4 receptor alpha, a subunit shared by IL13 and IL4 receptors.This subunit serves as a primary IL13-binding subunit of the IL13receptor, and may also be a component of IL4 receptors. Thisprotein has been shown to bind tyrosine kinase TYK2, and thus maymediate the signaling processes that lead to the activation ofJAK1, STAT3 and STAT6 induced by IL13 and IL4. [provided byRefSeq].
PubMed ID:http://aac.asm.org/content/26/5/689.abstract


IL13 Antibody

Product Name: IL13 Antibody
Species Reactivity: Human
Tested Applications: IF, IHC-P, WB
Applications: For WB starting dilution is: 1:1000For IF starting dilution is: 1:10~50For IHC-P starting dilution is: 1:10~50
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 16 kDa
Immunogen: This IL13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-146 amino acids from the C-terminal region of human IL13.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 314-13-6
Product: Vps34-IN-1
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.43 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Interleukin-13, IL-13, IL13, NC30
Accession NO.: P35225
Protein Ino: 239938644
Official Symbol: IL13
Geneid: 3596
Background: This gene encodes an immunoregulatory cytokine producedprimarily by activated Th2 cells. This cytokine is involved inseveral stages of B-cell maturation and differentiation. Itup-regulates CD23 and MHC class II expression, and promotes IgEisotype switching of B cells. This cytokine down-regulatesmacrophage activity, thereby inhibits the production ofpro-inflammatory cytokines and chemokines. This cytokine is foundto be critical to the pathogenesis of allergen-induced asthma butoperates through mechanisms independent of IgE and eosinophils.This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster onchromosome 5q, with this gene particularly close to IL4. [providedby RefSeq].
PubMed ID:http://aac.asm.org/content/26/5/686.abstract


IL12_2 Antibody

Product Name: IL12_2 Antibody
Species Reactivity: Human
Tested Applications: IHC-P, WB
Applications: For FACS starting dilution is: 1:25For WB starting dilution is: 1:1000For IHC-P starting dilution is: 1:10~50
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 97 kDa
Immunogen: This IL12_2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 756-783 amino acids from the C-terminal region of human IL12_2.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 463130
Product: LMK-235
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Interleukin-12 receptor subunit beta-2, IL-12 receptor subunit beta-2, IL-12R subunit beta-2, IL-12R-beta-2, IL-12RB2, IL12RB2
Accession NO.: Q99665
Protein Ino: 12229836
Official Symbol: IL12RB2
Geneid: 3595
Background: The protein encoded by this gene is a type I transmembraneprotein identified as a subunit of the interleukin 12 receptorcomplex. The coexpression of this and IL12RB1 proteins was shown tolead to the formation of high-affinity IL12 binding sites andreconstitution of IL12 dependent signaling. The expression of thisgene is up-regulated by interferon gamma in Th1 cells, and plays arole in Th1 cell differentiation. The up-regulation of this gene isfound to be associated with a number of infectious diseases, suchas Crohns disease and leprosy, which is thought to contribute tothe inflammatory response and host defense.
PubMed ID:http://aac.asm.org/content/26/5/683.abstract


IL12RB1 Antibody

Product Name: IL12RB1 Antibody
Species Reactivity: Human
Tested Applications: ELISA, WB
Applications: ELISA: antibody detection limit dilution 1:8000. Western Blot: Approx 100kDa band observed in Human Peripheral Blood Mononucleocytes lysates (calculated MW of 73.1kDa according to NP_005526.1). The observed molecular weight corresponds to the glycosylated form. Recommended concentration: 0.3-1μg/ml.
User Note:
Predicted Molecular Weight:
Immunogen: IL12RB1 antibody was raised against a 13 amino acid synthetic peptide near the Internal region of IL12RB1.
Host Species: Goat
Purification: IL12RB1 antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Physical State: Liquid
CAS NO.: 31842-01-0
Product: 1-Methyl-7-nitroisatoic anhydride
Buffer: IL12RB1 antibody is supplied in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin.
Concentration: 500 ug/mL
Storage Conditions: Aliquot and store at -20˚C. Minimize freezing and thawing.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: IL12RB1, MGC34454, interleukin-12 receptor beta-1 chain, interleukin 12 receptor, beta 1, IL-12R-BETA1, IL12RB, IL-12 receptor beta component, CD212, IL12R
Accession NO.: NP_005526.1
Protein Ino: 5031785
Official Symbol: IL12RB1
Geneid: 3594
Background:
PubMed ID:http://aac.asm.org/content/26/5/678.abstract


IL12B Antibody

Product Name: IL12B Antibody
Species Reactivity: Human
Tested Applications: ELISA, IHC-P, WB
Applications: ELISA: antibody detection limit dilution 1:16000. Western Blot: Approx 37kDa band observed in Human Liver lysates (calculated MW of 37.2kDa according to NP_002178.2). Recommended concentration: 0.1-0.3μg/ml. Immunohistochemistry: In paraffin embedded Human Colon shows cytoplasm staining of individual cells between columns. In paraffin embedded Human Kidney shows cytoplasm staining of epithelial cells of some DCT. Recommended concentration, 4-6μg/ml.
User Note:
Predicted Molecular Weight:
Immunogen: IL12B antibody was raised against a 15 amino acid synthetic peptide near the internal region of IL12B.
Host Species: Goat
Purification: IL12B antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Physical State: Liquid
CAS NO.: 319-89-1
Product: GSK4112
Buffer: IL12B antibody is supplied in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin.
Concentration: 500 ug/mL
Storage Conditions: Aliquot and store at -20˚C. Minimize freezing and thawing.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: IL12B, interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40), CLMF, CLMF2, IL-12B, NKSF, NKSF2, IL12, subunit p40, p40, interleukin 12, interleukin 12B, interleukin-12 beta chain, natural killer cell stimulatory factor, 40 kD subunit, natural killer cell stimulatory factor-2
Accession NO.: NP_002178.2
Protein Ino: 24497438
Official Symbol: IL12B
Geneid: 3593
Background:
PubMed ID:http://aac.asm.org/content/26/5/673.abstract


Il12 beta Antibody

Product Name: Il12 beta Antibody
Species Reactivity: Mouse, Rat
Tested Applications: ELISA, WB
Applications: ELISA: antibody detection limit dilution 1:4000. Western Blot: Approx 37kDa band observed in Mouse Spleen and Rat Liver lysates (calculated MW of 38.2kDa according to Mouse NP_032378.1 and 38.4kDa according to Rat NP_072133.1). Recommended concentration: 1-3μg/ml.
User Note:
Predicted Molecular Weight:
Immunogen: Il12 beta antibody was raised against a 12 amino acid synthetic peptide near the internal region of Il12 beta.
Host Species: Goat
Purification: Il12 beta antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Physical State: Liquid
CAS NO.: 32780-64-6
Product: Ro 5126766
Buffer: Il12 beta antibody is supplied in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin.
Concentration: 500 ug/mL
Storage Conditions: Aliquot and store at -20˚C. Minimize freezing and thawing.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: IL12B, interleukin 12B, RP23-388G23.1, Il-12b, Il-12p40, Il12p40, p40, IL-12 p40, IL-23 subunit p40
Accession NO.: NP_032378.1
Protein Ino: 6680397
Official Symbol: l12b
Geneid: 16160 (mouse); 64546 (rat);
Background:
PubMed ID:http://aac.asm.org/content/26/5/670.abstract