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. van Dijk SC, Smulders YM, Enneman AW, Swart KM, van Wijngaarden JP, et al. Homocysteine level is linked with aortic stiffness in elderly: cross sectional final results from the B-PROOF study. J Hypertens 31: 952959. 36. London GM, Asmar RG, O’Rourke MF, Safar ME, Purpose Project Investigators Mechanism of selective systolic blood pressure reduction 37. 38. 39. 40. 41. 42. 43. 44. 45. 46. 47. 48. right after a low-dose mixture of perindopril/indapamide in hypertensive subjects: comparison with atenolol. J Am Coll Cardiol 43: 9299. Sharman JE, Davies JE, Jenkins C, Marwick TH Augmentation index, left ventricular contractility, and wave reflection. Hypertension 54: Met-Enkephalin site 10991105. Tabara Y, Yuasa T, Oshiumi A, Kobayashi T, Miyawaki Y, et al. Effect of acute and long-term aerobic exercise on arterial stiffness in the elderly. Hypertens Res 30: 895902. Filipovsky J, Ticha M, Cifkova R, Lanska V, Stastna V, et al. Significant artery stiffness and pulse wave reflection: results of a population-based study. Blood Press 14: 4552. Katsuda S, Miyake 12926553 suppressed below the detection limit of presently readily available diagnostic assays. Nevertheless, even within the settings of optimal therapy, residual low-level viremia persists inside a substantial subset of sufferers. Because monitoring of ultra-low plasma viremia is technically difficult, and it is unclear irrespective of whether the low-level viremia has an effect on long-term therapy response, new diagnostic markers and tools will be required to assistance HIV care and clinical guidance with the subsequent generation of antiretroviral therapies. Not too long ago, cell-associated HIV-1 R.. van Dijk SC, Smulders YM, Enneman AW, Swart KM, van Wijngaarden JP, et al. Homocysteine level is linked with aortic stiffness in elderly: cross sectional outcomes from the B-PROOF study. J Hypertens 31: 952959. 36. London GM, Asmar RG, O’Rourke MF, Safar ME, Explanation Project Investigators Mechanism of selective systolic blood pressure reduction 37. 38. 39. 40. 41. 42. 43. 44. 45. 46. 47. 48. following a low-dose mixture of perindopril/indapamide in hypertensive subjects: comparison with atenolol. J Am Coll Cardiol 43: 9299. Sharman JE, Davies JE, Jenkins C, Marwick TH Augmentation index, left ventricular contractility, and wave reflection. Hypertension 54: 10991105. Tabara Y, Yuasa T, Oshiumi A, Kobayashi T, Miyawaki Y, et al. Effect of acute and long-term aerobic exercising on arterial stiffness in the elderly. Hypertens Res 30: 895902. Filipovsky J, Ticha M, Cifkova R, Lanska V, Stastna V, et al. Massive artery stiffness and pulse wave reflection: results of a population-based study. Blood Press 14: 4552. Katsuda S, Miyake 15481974 M, Kobayashi D, Hazama A, Kusanagi M, et al. Does the augmentation index of pulse waves actually raise with progression of atherosclerosis An experimental study with hypercholesterolemic rabbits. Am J Hypertens 26: 311317. Hughes AD, Park C, Davies J, Francis D, McG Thom SA, et al. Limitations of augmentation index inside the assessment of wave reflection in normotensive healthy folks. PLoS One eight: e59371. McEniery CM, Yasmin, Hall IR, Qasem A, Wilkinson IB, et al. Normal vascular aging: differential effects on wave reflection and aortic pulse wave velocity: the Anglo-Cardiff Collaborative Trial. J Am Coll Cardiol 46: 17531760. Sundstrom J, Sullivan L, D’Agostino RB, Jacques PF, Selhub J, et al. Plasma homocysteine, hypertension incidence, and blood pressure tracking: the Framingham Heart Study. Hypertension 42: 11001105. Eikelboom JW, Hankey GJ, Anand SS, Lofthouse E, Staples N, et al. Association between high homocysteine and ischemic stroke resulting from significant and small artery disease but not other etiologic subtypes of ischemic stroke. Stroke 31: 10691075. Nygard O, Vollset SE, Refsum H, Stensvold I, Tverdal A, et al. Total plasma homocysteine and cardiovascular risk profile: the Hordaland Homocysteine Study. JAMA 274: 15261533. Lim U, Cassano PA Homocysteine and blood stress within the Third National Health and Nutrition Examination Survey, 19881994. Am J Epidemiol 156: 11051113. Sutton-Tyrrell K, Bostom A, Zeigler Johnson C High homocysteine levels are independently associated with isolated systolic hypertension in older adults. Circulation 96: 17451749. Tsai JC, Kuo HT, Chiu YW, Hwang SJ, Chuang HY, et al. Correlation of plasma homocysteine level with arterial stiffness and pulse pressure in hemodialysis individuals. Atherosclerosis 182: 121127. 7 ~~ ~~ Present antiretroviral therapy efficiently suppresses HIV-1 plasma viremia by inhibiting viral replication. In most sufferers, plasma viremia is 12926553 suppressed under the detection limit of at the moment readily available diagnostic assays. Having said that, even within the settings of optimal therapy, residual low-level viremia persists within a significant subset of patients. Mainly because monitoring of ultra-low plasma viremia is technically difficult, and it is unclear irrespective of whether the low-level viremia has an effect on long-term therapy response, new diagnostic markers and tools might be needed to help HIV care and clinical guidance using the next generation of antiretroviral therapies. Not too long ago, cell-associated HIV-1 R.

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